NURS 5335 Fam 2 ABX/UTI Practice Quiz With Latest Solutionas

How do PCN and cephalosporins work - By weakening the cell wall and promoting lysis and death Bactericidal drugs are - Directly lethal to bacteria at achievable concentrations Why are narrow spectrum ABX preferred over broad spectrum ABX - Broad spectrum ABX do the most to facilitate emergency of resistance How does bacterial resistance develop with PCN? - -Production of PCN binding proteins that have low affinity for PCN -Inability of PCN to reach their target -Inactivation of PCN by bacterial enzyme Mary is a 20 year old female you have diagnosed her with strep throat. She has had an anaphylactic reaction to PCN. Which ABX is appropriate? - Azithromycin What are penicillinases - Beta-lactamases that act selectively on PCN Penicillinase-Resistant PCN - -Naficillin -Dicloxacillin -Oxacillin Broad spectrum PCN (aminopenicillins) - -Amoxicillin -Ampicillin Extended spectrum PCN (antipseudomonal) - -Ticarcillin -Pipercillin Beta-lactamase inhibitors - -Clavulanic acid -Sulbactam