CSOWM Metabolic and Bariatric Surgery
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Bariatric & Metabolic Surgery Procedures
🗸🗸: Group of surgical procedures that impact the physiological regulation of body weight and
improve morbidity and mortality rates
Purely restrictive weight loss surgery
🗸🗸: Laparoscopic adjustable gastric band (LAGB)
Weight loss surgeries that are combination (Malabsorptive & restrictive) -Gastric manipulation,
causing some restriction & neural/hormonal)
🗸🗸: Sleeve gastrectomy (SG) & Roux-en-Y Gastric bypass (RYGBP)
Bypass surgery that is combination of malabsorptive/restriction and of both macronutrients &
micronutrients
🗸🗸: Biliopancreatic Diversion (BPD/DS)
, 2
Cholecystokinin (CCK)
🗸🗸: Hormone secreted by the duodenum; suppresses appetite and levels decrease during dieting
and weight loss
Glucose-dependent insulinotropic polypeptide (GIP)
🗸🗸: Hormone secreted by the duodenum and jejunum; normal function for energy storage;
Levels increase during dieting and weight loss
Ghrelin
🗸🗸: Hormone from the gastric fundus; Functions to stimulate appetite for high fat, high sugar
foods; Levels increase during diet and weight loss
Glucagon-like peptide 1 (GLP-1)
🗸🗸: Hormone secreted in the ileum of the small I; Functions to suppress appetite and increase
satiety; Levels have a decreased functionality with diet and weight loss
Peptide YY (PYY)
🗸🗸: Hormone secreted in the distal small I; Suppresses appetite; There is a decrease in this
hormone found in obese persons with weight loss
, 3
Insulin
🗸🗸: Hormone secreted from the beta cells of the pancreas; Functions to regulate energy balance
and signal satiety in the brain; There is resistance to this hormone in obese persons; Levels
decrease after dieting
Leptin
🗸🗸: Hormone secreted from the adipocytes; Regulates energy balance & suppresses appetite;
Levels decrease during weight loss
Metabolic and bariatric surgery changes to gut hormones?
🗸🗸: The opposite of restrictive dieting
RYGB + SG changes in gut hormones
🗸🗸: They don't see a decrease in RMR; decrease in appetite and hunger; increase in satiety;
decrease in ghrelin, increase in GLP-1, PYY, CCK, and amylin
Amylin
🗸🗸: co-secreted with insulin by beta cells in response to nutrient stimuli. Delays nutrient uptake
and suppresses glucagon secretion after meals. Satiating effect.
LAGB + Hunger hormones