Introduction to Clinical Pharmacology-Drugs for Gastrointestinal Problems Review Questions and Answers

What types of drugs prevent or control nausea and vomiting? A. Antiemetic drugs B. Antimotility drugs C. Antidiarrheal drugs D. Antipropulsion drugs Antiemetic drugs *these drugs control nausea and prevent vomiting which often occur together, and the same drugs are used for both problems Which common drug for nausea/vomiting is a 5-HT3-receptor antagonist? A. Ondansetron B. Promethazine C. Scopolamine D. Metoclopramide Ondansetron *Ondanestron (Zofran, Zuplenz) is a 5-HT3 receptor antagonist that reduces or halts nausea and vomiting by blocking serotonin (5-HT3) receptors in the intestinal tract What specific problem can develop in a patient who has been prescribed both a 5-HT3 receptor antagonist and a phenothiazine? A. Bleeding B. Muscular tremors C. Serotonin syndrome D. Cardiac dysrhythmias Cardiac dysrhythmias *when combined with phenothiazine drugs, the patient may experience cardiac dysrhythmias You are caring for a patient who is taking a substance P/neurokinin1 (NK1) receptor antagonist. Which laboratory finding would suggest the patient is experiencing an adverse reaction to this class of drugs? A. Decreased magnesium level B. Increased blood glucose level C. Increased serum creatinine level D. Decreased white blood cell count Decreased white blood cell count