Introduction to Clinical Pharmacology Final Examination Questions and Answers

Prostaglandins INFLAMMATORY RESPONSE Also have a role in the inflammatory response housekeeping actions in the tissues Prostaglandins INFLAMMATORY RESPONSE GI tract renal function, platelet aggregation consciousness and mental functions in the brain, and temperature regulation Prostaglandins INFLAMMATORY RESPONSE also cause erythma increase blood flow remove the vasoconstrictor effects of substances such as norepinephrine and angiotensin Antiinflammatory and analgesic agents ASPIRIN greater antiinflammatory action than other salicylates and is preferred in the treatment of many problems Antiinflammatory and analgesic agents ASPIRIN emergency antiplatelet drug to use in patients who are having myocardial infarction (MI) or to prevent other MIs or strokes. Antiinflammatory and analgesic agents ASPIRIN analgesia in generalized pain analgesic but not an NSAID because it has no antiiinflammatory properties Salicylates ACTION pain and inflammatory processes through a depressant effect on the central and peripheral pain receptors, by blocking the production of cyclooxygenase an ezyme that is necessary for the production of prostagladins Salicylates USES stopping prostagladin treatment of mild to moderate pain slow the clumping of platelets Salicylates USES if it is suspected that a patient is having a heart attack (MI), they are to chew up at least one regular 325 mg aspirin