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Pharmacology Psychiatric (Psycho Pharm) Mental Health Nurse Practitioner Exam Combined Questions & Revised Correct Answers

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Pharmacology Psychiatric (Psycho Pharm) Mental Health Nurse Practitioner Exam Combined Questions & Revised Correct Answers What are the five factors that influence absorption? - ANSWER : Gastric emptying Time of contact with intestinal wall Bowel perfusion Food Formation of non-absorbable complexes Explain the hepatic first pass. - ANSWER : Part of the drug is metabolized by the liver before it reaches the blood. Explain bioavailability. - ANSWER : Percentage of administered drug that reaches systemic circulation. Name the 3 highly water-soluble drugs. - ANSWER : Lithium, Amisulpride, Paliperidone What are the 7 inhibitors of CYP? - ANSWER : Paroxetine, Fluoxetine, Fluvoxamine, Fluconazole, Ciprofloxacin, Ritonavir, Grapefruit juice What are the 6 inducers of CYP? - ANSWER : Carbamazepine, Phenytoin, Phenobarbital, Primidone, smoking, St-John's Wort

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