Peptic Ulcer Disease Exam Questions With 100% Correct Answers

Peptic Ulcer Disease Exam Questions With 100% Correct Answers peptic ulcer disease - answera break in the mucous lining of the GI tract where it comes in contact with gastric juice -is a chronic health problem -may occur in any area of the GI tract exposed to acid-pepsin secretions including the esophagus stomach and doudenum duodenal ulcers - answerare the most common type -which occur in the duodenum. -usually develops between the age of 30 and 55 -more common in men than in women. gastric ulcers - answeroccur in the stomach more often affect older clients between the age of 55 and 70. ulcers - answerare more common in people who smoke and who are chronic users of NSAIDS etiology of peptic ulcer disease. - answerMay be due to any of the following: H pylori infection Drugs (NSAIDS) Lifestyle factors (smoking) Severe physiologic distress (critically ill patients in the ICU) Hypersecretory states - uncommon (Zollinger-Ellison) Genetic factors ulcer - answerdevelops when the mucosal barrier is unable to protect the mucosa from damage by the hydrochloric acid and pepsin, the gastric digestive juice. helicobacter pylori infection - answerfound in about 70% of individuals who have PUD -it is unique in colonizing the stomach -it is spread individual to individual(oral-oral or fecal-oral) -it also contributes to ulcer formation in severa; ways. -usual site of infection is gastric mucosa but can also contribute to duodenal ulcers due to increased production of gastric acid associated with H.pylori infection. -it can occur in several members of the family especially when the family's water supply is contaminated. pathophysiology of pud - answerMucosal barrier protects gastric mucosa Ulcer develops when barrier can't protect mucosa from digestive juices Hydrochloric acid and pepsin H pylori found in 70% of those with PUD A little history on H pylori.... NSAIDS - answer-Systemic and topical mechanisms of injury -Inhibit prostoglandins( prostaglandins are necessary for maintaining the gastric mucosal barrier -Exert topical injury by damaging cells themselves pathophysiology of PUD - answerulcers may affect the esophagus, stomach or duodenum Ulcers may be superficial or deep Most duodenal ulcers in proximal portion close to pylorus Gastric ulcers mostly in lesser curvature of stomach near pylorus At risk for developing gastric cancer duodenal ulcers - answeris the most common usually develop in the proximal portion of the duodenum close to the pylorus -they are sharply demarcated and usually less than 1 cm in diameter. gastric ulcers - answerit is mostly in lesser curvature of stomach near pylorus At risk for developing gastric cancer PUD - answermay be chronic with spontaneous remissions and exacerbations. -exacerbations of the disease may be associated with trauma, infection or other physical or psychological stressors. -caffeine and alcohol consumption may exacerbate the disease. risk factors of PUD - answerchronic H pylori infection chronic NSAID use