IACUC Community Member Questions with well explained answers

Which of the following statements is true regarding the three-year (triennial) review of animal activities (protocols)? - Answer-PHS Policy mandates a review according to regulations and policies in place at the time of the triennial review, whether or not new protocol forms are completed. To comply with both the Animal Welfare Regulations (AWR) and PHS Policy, the IACUC must do which of the following after the initial review and approval of a protocol? - Answer-Perform an annual review prior to the first and second approval anniversaries, and perform a triennial review prior to the third anniversary. true or false? The USDA requires the investigator to reconsider alternatives annually. - Answer-false Which of the following statements is true about modifications or amendments to animal protocols after IACUC approval? - Answer-Significant changes must be reviewed and approved by the IACUC before they are implemented. The two IACUC review methods recognized by the Animal Welfare Regulations (AWR) and PHS Policy are: - Answer-Full committee review and designated member review. Although opinions vary about the level of detail needed in IACUC minutes, a typical standard is that IACUC minutes: - Answer-Should allow an outside observer to verify that deliberations occurred and understand the outcomes of those deliberations. Regarding IACUC use of review outcomes such as "approval pending," "conditional approval," or "deferred," which of the following is false? - Answer-These terms are defined by the PHS Policy to be synonymous with "Requiring modifications in order to secure approval." Which of these IACUC protocol review outcomes is recognized in the Animal Welfare Regulations (AWR) and PHS Policy? - Answer-Approve, require modifications in (to secure approval), and withhold approval. The best practice sequence of events for a designated member review by the IACUC is: - Answer-Review materials are sent to all voting members; full committee review is not requested by any member; the IACUC chair assigns one or more IACUC members as designated reviewers.