BCH 403 Exam 2 Questions with Complete Solutions
Why are enzymes really good catalysts? Correct Answer-Because enzyme active sites have evolved to catalyze reactions with maximum efficiency by using several catalytic mechanisms simultaneously Enzymes exhibit maximal activity under what kind of conditions? Correct Answer-Mild conditions, like conditions that exist in cells. Why are enzymes categorized as being extremely specific? Correct Answer-Because an enzyme usually catalyzes ONLY the reaction involving "its" substrate, even though cell may contain comparable levels of related compounds Do enzymes release side products? Correct Answer-No they do not release side products Hydrolysis of Ester Correct Answer-Oxygen of water is a nucleophile which attacks electrophilic carbonyl of the ester What are the two ways that would be helpful in the reorganization of bonding that occurs in the transition state of the hydrolysis of ester reaction? Correct Answer-IF: a) A pos charge could be brought in to stabilize developing neg charge on carbonyl oxygen (increase electrophilicity of carbonyl carbon)
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