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Genetics Chapter 17: Control of Gene Expression in Eukaryotes

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In-depth Genetics lecture 18 notes over Control of Gene Expression in Eukaryotes. (Pictures, examples, and simplified in-depth information over chapters)

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Lecture 18
Control of Gene Expression
in Eukaryotes




BI333: General Genetics
Dr. Matt Arterburn
Department of Biology

,Control Points for Eukaryotic Genes

cytoplasm Arrangements of genes
in the genome &
& copy
copy ##
nucleus


DNA I. Chromatin Structure &
Chemical Modification

II. Transcription
RNA
III. RNA Processing
mRNA


IV. Nuclear Export

V. Translation
Protein
VI. Protein Modification
& Trafficking

, POSITION EFFECTS OF GENES
• Different regions of the genome have different levels of expression (ex:
heterochromatin and euchromatin)

• Ex: movement of red pigment gene for Drosophila eye color to a region
near heterochromatin

• Lowers pigment gene expression and causes a partial “white eye” mutant



• Cells can control expression
by moving genes to other
regions (their position in the
genome can determine their
expression levels)

• This is used by many
organisms in specific gene
expression strategies

Connected book
 image
Benjamin A. Pierce Genetics: A Conceptual Approach
Publisher: 2012 ISBN: 9781429232524 Edition: Unknown

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Uploaded on
May 4, 2024
Number of pages
23
Written in
2023/2024
Type
Class notes
Professor(s)
Dr. arterburn
Contains
Lecture 18
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