ATI PHARMACOLOGY CHAPTER 1 QUESTIONS WITH CORRECT ANSWERS|100% verified

ATI PHARMACOLOGY CHAPTER 1 QUESTIONS WITH CORRECT ANSWERS phases of pharmacokinetics CORRECT ANSWER 1. Absorption 2. Distribution 3. Metabolism 4. Excretion Absorption CORRECT ANSWER The transmission of medications from the location of administration to the bloodstream. Rate of absorption determines how soon the medication will take effect. The amount of medication the body absorbs determines the intensity of its effects. The route of administration affects the rate and amount of absorption. Common routes of administration CORRECT ANSWER oral, sublingual, inhalation, rectal, vaginal, topical, intradermal, subcutaneous (SC), intramuscular (IM), and intravenous (IV) Pharmacokinetics CORRECT ANSWER The process by which drugs are absorbed, distributed within the body, metabolized, and excreted. oral CORRECT ANSWER Mouth. Barriers: med must pass through the epithelial cells that line the GI tract. Absorption pattern: varies d/t stability and solubility of the medication, GI pH and emptying time, food in the stomach, concurrent meds, enteric/liquid). sublingual CORRECT ANSWER under the tongue Barriers: swallowing before absorption Absorption pattern: quick absorption systematically through mucous membranes Other mucous membranes (rectal, vaginal) CORRECT ANSWER barriers: presence of stool/infectious material can prevent absorption absorption pattern: easily absorbed w/ local and systemic effects Inhalation CORRECT ANSWER breathing in Barriers: inspiratory effort Absorption pattern: rapid through alveolar capillary networks Intradermal/topical CORRECT ANSWER barriers: epidermal cells closely packed absorption pattern: -Slow, gradual absorption -Effects primarily local, but systemic as well, especially with lipid soluble medications passing through subcutaneous fatty tissue