Bcacp - Oncology Exam Questions And Answers 2024.

most common cancers? (3) lung cancer, breast cancer, prostate cancer Best 2 guidelines? NCCN and ASCO Mutations for lung cancer? Kras, EGFR others implications of K-ras mutation? nonresponsive to anti-EGFR therapties any harm in continuin gsmoking during treatmetn? YES waht % of SCLC and NSCLC? 14% SCLC (more active, but more responsive, but not durable) Usualy treatments for SCLC (more active, resonsive to traditional) cisplatin, etoposide, irinotecan SCLC what to do to prevent brain mets brain radiation with chemo Goal of limited SCLC? extensive SCLC? cure, palliative One of the most prominent emetogenicity? cisplatin Dose limiting toxicity of irinotecan , treat? acute and delaty diarrhea (I ran to the can), treat with atropine preferred treatment NSCLC cisplatin doublets (need to have good ECOG) ECOG 3 and 4 patients sleeping all day etc, not getting out of bed Squampouis stage IV NSCLC cisplatin + gemcitabine Nonsquamous stage IV nsclc cisplatin premetrexed (others based on mutations) Gemcitabine dose limiting toxicity? neutropenia thrombocyto Premetrexed toxicity? issues? Need folic acid and B12 to revent toxicitis Afatinib, role? alternative if not the correct eGFR mtation? ORAL EGFR mutations (19 and 21), erlotinib Afatinib tox? Diarrhea, rash (90%), mucositis, nail changes what do you need before using erlotinib afatinib? mutation info most common rf for breast cancer? age (FH and genetics not as prominent) screening for breast cancer annual after age 40, every 2 years after age 50 median survival for stage IV? 3 years comon AE o fthe taxanes? neuropathy page 39, 40AE of the 5 drugs ... If HER2+ good options trastuzumab pertuzumab docetaxel Prostate cancer growth and survival? ver slow growing, 15 year survival 91% USPSTF recommends against PSA screening risk outweighs benefit CINV risk factors women, younger age, infrequent alcohol, anxiety, higher doses and cumulative doeses of chemo If highly emetogenic chemo? other know ... Role of ESA? tumor may grow quicker, if Hgb 10, and therapy WITHOUT cureative intent Definition febrile neutro ... proph abx for PP of infection? No, not adopted