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Multiple Sclerosis (MS) - ANSWER-autoimmune disorder where the body mistakenly attacks the brain and spinal cord; chronic degenerative disease of central nervous system; uncertain etiology
Demyelination - ANSWER-MS attacks the myelin sheath in multiple areas of the CNS resulting in formation of scar tissue or plaques; interferes w/ normal nerve conduction & impulse transmission
Causes of MS? - ANSWER-No known cause for MS, however, factors associated with development of the disease include heredity, autoimmune response, virus, and/or a combination of these factors.
How many Americans have MS? - ANSWER-Approximately 350,000 and every week approximately 200 people are diagnosed.
MS diagnosis in relation to the 37th parallel? - ANSWER-Prevalence is approximately 110-140 incidents per 100,000 in the population above the 37th parallel; below this line, rates run 57-78 cases per 100,000.
Location of the 37th parallel? - ANSWER-In the US, this is a line that runs east to west, passing roughly above N Carolina to Arizona and encompassing most of California.
Who is diagnosed with MS? - ANSWER-Caucasians more frequently and women.
MS lifetime risk? - ANSWER-1 in 400; potentially the most common cause of neurological disability in young adults.
Signs and symptoms of early stage MS? - ANSWER-Sensory dysfunctions, motor dysfunctions, cerebellar dysfunctions, reduced cognitive functions, other CNS signs. Several occur paroxysmally.
Signs and symptoms of advanced stage MS? - ANSWER-Described in stages primary, secondary and tertiary. See table in book, chapter 3, page 4 for detail.
What is the most common area of the CNS attacked by MS? - ANSWER-Spinal cord - approximately 42% of all occurrences.
Sensory complaints - ANSWER-Decreased sensation involving the limbs or the trunk including numbness, unpleasant feelings, Lhermitte's sign.