LATEST NR 507 WEEK 1 CASE STUDY

1. 3 levels of immunity - 1st line - physical, mechanical, & biochemical barriers 2. What is the first line of immunity defense - Physical, mechanical and biochemical barriers (innate or natural immunity) 3. Types of innate immunity - Physical, mechanical, biochemical barriers and inflammatory response 4. Intact skin & mucous membranes - 1st line - physical barriers 5. Flushing, sweeping, peristaltic action - 1st line - mechanical barriers 6. production of mucus, urine, tears, bile - 1st line - biochemical barriers 7. Presence of normal micro-biome - 1st line - biochemical barriers 8. What is the second line of immunity defense - The inflammatory response (innate or natural immunity) 9. define the inflammatory response - Nonspecific protection: Activated when the first line of defense is breached by injury or infection 10. Phagocytic white blood cells (WBC's) - 2nd line - inflammatory response 11. Chemical components or chemical mediators - 2nd line - inflammatory response 12. What line of defense provides immediate and localized protection - 2nd line - inflammatory réponse 13. What is the third line of immunity - Lymphocyte production (Adaptive or acquired response) 14. Slower acting systemic protection - 3rd line - lymphocyte production 15. Specialized WBC's: lymphocytes - 3rd line - lymphocyte production 16. Define the 3rd line of defense - Specific protection: Activated to provide back-up to 2nd line of defense 17. Types of white blood cells - Neutrophils (PMNs), eosinophil, basophils, monocytes (macrophages), lymphocytes, mast cells, natural killer cells 18. Types of chemical mediators - Histamine, leukotriene, interleukins (ILs), interferons (IFN), kinins, prostaglandins, complement (C') 19. What is our most important immune defense? - Skin and membranes 20. Four classic signs of inflammation - Heat, redness, swelling, pain