WGU Biochemistry OA Review Questions And Answers

WGU Biochemistry OA Review Questions And Answers Types of enzyme regulation - Phosphorylation Dephosphyorylation Feedback inhibition Competitive inhibitor Non competitive inhibitor chaperones - protein helpers that help folding of complicated protein structure they bind to newly made polypeptides and enable proper folding Protein structures are stablized by: - the hydrophobic effect with van der waals interactions Disulfide bonds can be found in: - proteins secreted from a cell: insulin structural purpose proteins: keratin skin hair nails Denaturation - the los of secondary, teritary, and quatirary structure-primary structure remains intact. They do lose their ability to fx properly though Why does denaturation happen? - Heat exposes hydrophobic bonds to water outside of a protein cauisng the amino acid to clump together and aggregate Hydrogen and Ionic bonds can be broken how? - by changes in salt and PH concentration -protein doesn't aggregate but it does cause protein to not be fxn. How can disulfide bonds be broken? - by reducing agents (cals) Heat breaks which bonds? - Hydrophobic interactions (effect) Changes in PH changes which bonds? - Ionic and hydrogen bonds High concentrations of NA+ affects which bonds? - Ionic and H+ bonds Primary structure is held together by which bonds? - peptide bonds Secondary structure is held together by which bonds? - Hydrogen bonds Teritary structure is held together by which interactions? - R-side chain interactions What enviornmental factors affect enzyme activity? - Temp PH substrate concentrations Coenzymes competitive inhibition - a molecule that resembles the normal sub