NCLEX Meds (140 Must Know) 2023 WITH COMPLETE SOLUTIONS GRADED A+ (PROVIDES FULL EXPLANATIONS)

Alteplase (t-PA) - ANSWER *class*: thrombolytics *Indication*: MI, acute ischemic stroke, occluded central lines *Action*: converts plasminogen to plasmin which degrades the fibrin found *Nursing Considerations*: - contraindicated in active bleeding -monitor for anaphylaxis - use caution with uncontrolled hypertension Atorvastatin (Lipitor) - ANSWER *class*: lipid-lowering agent *Indication*: management of high cholesterol (hypercholesterolemia), primary prevention of cardiovascular disease *Action*: lowers total cholesterol as well as LDL while slightly increasing HDL. Inhibits HMG-CoA reductase which plays a role in the liver in cholesterol formation *Nursing Considerations* - contraindicated in active liver disease - may cause rhabdomyolysis - monitor serum cholesterol - monitor liver function tests, renal function Acetaminophen (Tylenol) - ANSWER *class*: antipyretic, non-opioid analgesic *Indication*: pain, fever *Action*: inhibit the synthesis of prostaglandins which play a role in transmission of pain signals and fever response *Nursing Considerations*: