NURS 5334Pharm StudyGuide Quiz 1Latest UpdateBest ExamSolution Graded A+

NURS 5334Pharm StudyGuide Quiz 1Latest UpdateBest ExamSolution Graded A+NURS 5334 PHARM MODULE 1 • What are the BON rules and regulations for prescriptive authority for the advance practice nurse? • Texas is very restricted • Describe the pharmacokinetic processes of absorption, distribution, metabolism and elimination and how differences in these areas affect drug action. • Absorption • Drug’s movement from the site of administration into the blood. • Distribution • Drug’s movement from the blood into the interstitial space of tissues and from there into cells. • Metabolism • Biotransformation is the enzymatically mediated alteration of drug structure. • Elimination • Combination of metabolism and excretion • Discuss the impact of food on drug absorption, drug metabolism and on drug toxicity and action—as well as the timing of drug administration. LIFESPAN • Hepatic metabolism and GFR increase during pregnancy, dosages of some drugs may need to be increased. • Rate of albumin to water decreases • Third trimester: Renal blood flow is doubled and renal excretion is accelerated (drugs excreted rapidly) • Tone and mobility of bowel decrease • Prolongation of drug effects Total (½ life increases) Understand stages of development in pregnancy onlystudents 12/4/23, 4:44 PM NURS 5334 Pharm Study Guide Quiz 1 Latest Update Best E… about:blank 3/83 • Conception: through week 2 • Embryonic period: week 3-week 8 a) Gross malformations can be produced by teratogens • Fetal period: week 9-delivery • Understand pregnancy labeling • 3 categories now a) Pregnancy, lactation, male & female reproductive potential • How do you decrease risk in the infant during breastfeeding? • Take meds immediately after breastfeeding, avoid drugs that have long half-lives, choose drugs that tend to be excluded from milk, avoid drugs that are known to be hazardous. • How do pediatric patients differ in their response to medications? • Absorption a) Oral? • Neonates: drug remain in the stomach longer which increases the levels, low acidity can affect the absorption of acid labile drugs b) Parenteral? • Reponses are slow and erratic. • Infancy: absorption is more rapid than i