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  • BCOP Cytogenetics Qurestion And Answer
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BCOP cytogenetics Qurestions And Answers

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BCOP cytogenetics Qurestions And Answers Philadelphia chromosome - ANS-t (9;22) APL gene - ANS-PML-RARA fusion gene t (15, 17) cytogenics that automatically result in diagnosis of AML regardless of blast % - ANS-t (8, 21), inv (16), t (16, 16) t (15,17) which mutation is it appropriate to use lenalidomide in MDS - ANS-del (5q) Which mutation causes resistance in CML to imatinib, dasatinib, nilotinib, bosutinib? - ANS-T315I Prognosis in IDH mutated CNS malignancies - ANS-Associated with better PFS and OS 1p/19q codeletion is always associated with which mutation in CNS malgnancies and what is is prognosis - ANS-Always occurs with IDH mutation and are associated with improved survival Associated with improved response to PCV regimen (procarbazine, lomustine, vincristine) What is the significance of MGMT methylation in CNS malignancies? -

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