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Exam (elaborations)
Steps in Excitation-Contraction Coupling A+ Graded
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Step 1 Action potential spread along the sarcolemma to the T-tubules (transverse tubules) Step 2 Calcium is released into the sarcoplasmic reticulum (S.R.) Step 3 Calcium binds to actin and the blocking action of the tropomyosin is removed Step 4 Myosin heads attach to begin contraction Step 5 Calcium is removed and the binding sites on actin become blocked again by tropomyosin Step 6 Muscle relaxes
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