NR 566 / NR566 Advanced Pharmacology Final Exam Review 2024 (VERIFIED)

NR 566 / NR566 Advanced Pharmacology Final Exam Review 2024 (VERIFIED) Antacids MOA - Neutralize gastric acid to bring the pH above 3 and inactivate pepsin • which antacids have the highest absolute neutrophil count (ANC)? - sodium bicarbonate and calcium carbonate • When aminopenicillins are combined with beta-lactamase inhibitors - their spectrum in broadened • beta-lactamase inhibitors that can be combined with aminopenicillins - clavulanate, sulbactam, & tazobactam • Penicillinase-resistant penicillins drugs - Nafcillin - Oxacillin - Cloxacillin - Dicloxacillin - Methicillin • Penicillinase-resistant penicillins active against - Streptococcus, MSSA, some coagulase-negative staphylococci, peptostreptococcus • Anti-pseudomonal penicillin drugs - Piperacillin - Ticarcillin - combination: o piperacillin/taxobactam - ticarcillin/clavulanate • Anti-pseudomonal penicillins active against - gram (-) organisms • 1st generation cephalosporins drugs - Cephradine (Anspor) - Cefazolin (ancef) - Cefadroxil (Duricef) - Cephalexin (keflex) • What do calcium containing antacids needs for absorption? - vitamin D • Antacid Indications - hyperacidity, - PUD, GERD, Calcium deficiency, Chronic Renal failure, osteoporosis prevention • Monitoring after given antiviral for flu - no flu vaccine for 2 weeks before or 48 hours after antiviral is given • 1st line therapy for uncomplicated UTI - trimethoprim/sulfamethoxazole (Bactrim) • what causes ophthalmia neonatorum - chlamydia • patient education for albendazole & mebendazole - take with a high fat meal • patient education for ivermectin - take on empty stomach • patient education for ibendazole - don't use if pregnant; use back of contraceptive • Aminopenicillins Drugs - Amoxicillin - Ampicillin - Combinations: - Amoxicillin-clavulanate (Augmentin) • Antifungal (Antimycotics) classes - azoles - polyene macrolides - Allylamines - Nuclear Acid Synthesis inhibitors - Griseofulvin • Azoles - Triazoles drugs - fluconazole (Diflucan) - itraconazole (Onmel) - voriconazole (Vfend) - Clotrimazole - Ketoconazole - minonazole - terconazole - tioconazole • Polyene Macrolides drugs - amphotericin B - nystatin • Allylamines Drugs - Terbinafine (Lamasil) - Naftifine • Nuclear acid synthesis inhibitor drugs - Flucytosine • Fluoroquinolone older drugs - cipofloxacin (cipro) - norfloxacin (noroxin) - ofloacin (flovin) • Fluoroquinolones new drugs - gemifloxacin (factive) - levofloxacin (levaquin) - moxifloxacin (avelox) • Macrobid indication - UTI NR 566 / NR566 Advanced Pharmacology Final Exam Review | Rated A+ | Latest, 2021/2022| Complete Guide | Chamberlain College • the most common cause of Traveler's diarrhea - E. coli • PUD stepped-approach algorithm - Step 1: lifestyle modification/antacids - Step 2: H. pylori testing/PPI - Step 3 (uncomplicated): tx for H.pylori - Step 4 (uncomplicated): PPI continues for 8-12 weeks until healed - Step 5 (uncomplicated, low risk): no on-going therapy - Step 5 (uncomplicated, high risk): PPI or H2RA (smokers, 60, CPOD, CAD, hx of bleeding, ulcers or NSAIDs) - Step 3 (complicated, bleeding): refer to GI for endoscopy - Step 4 (complicated): tx for H. pylori - Step 5 (complicated): repeat endoscopy in 12 weeks to determine healing • what causes most diarrhea? - infection, food or drug ingestions, or inflammatory bowel disease NR 566 / NR566 Advanced Pharmacology Final Exam Review | Rated A+ | Latest, 2021/2022| Complete Guide | Chamberlain College NR 566 / NR566 Advanced Pharmacology Final Exam Review | Rated A+ | Latest, 2021/2022| Complete Guide | Chamberlain College • symptomatic treatment for viral URIs - decongestant - Tylenol - ASA - Motrin - increase fluid intake - cough drops - nasal saline spray - rest • 1st lines therapy for acute otitis media (AOM) & sinusitis