NUR 414 EXAM 2 QUESTIONS AND ANSWERS ALL CORRECT

NUR 414 EXAM 2 QUESTIONS AND ANSWERS ALL CORRECT Cellular immunity occurs when antibodies are produced by - Answer-native T cell lymphocytes Humoral immunity occurs when antibodies are produced by - Answer-native B cell lymphocytes T/F young children have bigger lymph nodes, tonsils, and thymus compared to adults - Answer-T 10 warning signs of primary immunodeficiency - Answer-1. 4 or more new ear infections w/in 1 year 2. 2 or more serious sinus infections w/in 1 year 3. 2 or more months on antibiotics w/ little effect 4. 2 or more pneumonias w/in 1 year 5. Failure of an infant to gain weight or grow normally 6. Recurrent, deep skin or organ abscesses 7. Persistent thrush in mouth or fungal infec. on skin 8. Need for IV antibiotics to clear infections 9. 2 or more deep-seated infections like sepsis 10. A family hx of primary immunodeficiency Hypogammaglobulinemia - Answer-Low or absent levels of one or more of the immunoglobulin classes Child does not form antibodies appropriately Treatment for hypogammaglobulinemia - Answer-IV immunoglobulin (IVIG) Wiskott-Aldrich syndrome - Answer-X linked genetic disorder that results in immunodeficiency, eczema, and thrombocytopenia This affects males only Treatment for Wiskott-Aldrich Syndrome - Answer-hematopoietic stem cell (bone marrow) transplantation Severe Combined Immune Deficiency - Answer-X linked or autosomal recessive disorder Absent B cell and T cell function Symptoms of SCID - Answer-- chronic diarrhea - failure to thrive - hx of infection in early infancy - persistent thrush - adventitious lung sounds r/t pneumonia - low levels of immunoglobulin Treatment for SCID - Answer-Gene therapy and bone marrow/stem cell transplant T/F Secondary immunodeficiencies result from something else like chronic illness, immunosuppressants, HIV, prematurity, etc. - Answer-T How to diagnose a child with HIV? - Answer-- PCR test (detects HIV DNA/RNA) - ELISA test (antibodies to HIV) - less than 30,000 platelets - low CD4 and ANC In an autoimmune disease, the body - Answer-manufactures T cells and antibodies against its own cells and organs Symptoms of systemic lupus erythematosus - Answer-- alopecia - anemia - arthritis - fatigue - lupus nephritis - photosensitivity - pleurisy - seizures - stomatitis - thrombocytopenia - skin rashes Juvenile Idiopathic Arthritis - Answer-Chronic synovial inflammation with joint effusion and erosion, destruction, and fibrosis - child experiences swelling, stiffness, and loss of motion Medications used to treat JIA - Answer-- NSAIDs - Corticosteroids - Cytotoxic agents - DMARDs