PHARMACOLOGY NURS 251 MODULE 9 EXAM QUESTIONS AND CORRECT ANSWERS PORTAGE LEARNING 2023/2024 GRADED A+.

PHARMACOLOGY NURS 251 MODULE 9 EXAM QUESTIONS AND CORRECT ANSWERS PORTAGE LEARNING 2023/2024 GRADED A+. 2 / 4 1. Initial medication for RA before special: DMARD (Disease modifying an-tirheumatic drug) not always effective 2. Recent hepatitis C treatment time: 3 months; 96% cure rate 3. HIV/AIDS virus destroys cells/immune system while pt asymptomatic: - CD4/T cells 4. Recombinant DNA technology: joining 2 DNA molecules & inserting into a hostorganism and generates products from human use 5. Biologics:specialty meds made from recombinant DNA technology; growth ofspecialty pharmacy industry. 6. Humoral immunity: immune response from B-cells + antibody production 7. Leukocytes that develop plasma cells & produce antibodies to bind toantigens: B-cells 8. Antibodies: molecules that bind/inactivate antigen molecules via formation ofantigen-antibody complex 9. immune response mediated byT cells/lymphocytes; collab w/humoral im-munity: cellmediated immunity 10. produces cytokines: T cells 11. Nonantibody proteins released by activated t cells upon contact w anti-gens. intercellular mediators of immune response.: cytokines 12. T helper cells: promote actions of immune system cells 13. cells limit immune response/balances helperT cells: T suppressor 14. differentiatedT cells that recognizes foreign antigens/destroys target cell- : Cytotoxic T cells 15. biologics that enhance/reduce immune response: immunomodulating drugs 16. immunomodulating drugs example: interferons, monoclonal antibodies, inter-leukin receptor antagonists/agonists, miscellaneous drugs. 17. drugs specifically treat cancer cells/avoids healthy cells and treats autoimmune inflammatory dz/RA; interferes w overactive immune response.- : immunomodulating drugs 18. proteins w antitumor, antiviral, immunomodulating properties; tx can-cer/viral 3 / 4 infections: interferons 19. interferons affects on immune system: restore/augment/inhibit function 20. interferon beta-1a drug; tx MS/slows progression physical disability: - Avonex or Rebif;s/e- flu like symptoms. 21. once weekly IM (interferon beta-1a): Avonex 22. 3x/week SUBQ (interferon beta-1a): Rebif 4 / 4 23. costly drugs created w recombinant DNA that specifically target cancer cells and treat RA/chron's/MS/organ tx: monoclonal antibodies;s/e- severe aller-gic inflam infusion rxn- premedicate b4. 24. ANTI TNF Monoclonal antibody prevents TNF molecules from binding to TNF cell surface/impacts inflammatory response; tx RA/chron's/ulcer coli- tis/plaque psioriasis/psoriatic arthritis.: Adalimumab (Humira);SC EVERY OTH-ER WEEK 25. ANTITNF Monoclonal antibody that worsens heart failure/cx in class 3 or 4.TX anklyosing spondylitis, chrons RA: Infliximab (Remicade) ; IV INFUSIONEVERY 6-8 WEEKS ONCE STABLE 26. Monoclonal antibody/anti-human vascular endothelial growth factor;(pro-tein that promotes new blood vessels in tumor/body tissues). Tx mets COL- ORECTAL cancer: Bevacizumab (Avastin); iv infusion q2weeks 27. Humanized monoclonal antibody derived from murine myeloma cells. Treats MS- inhibits leukocyte adhesion to alpha4 subunits of integrins. S/E rare brain viral infection ;FDA requires specific program: Natalizumab (Tysabri);IV infusion every 4 weeks. Anti-alpha4 integrin subunit. 28. Natural pt of immu