NURS 660 SUM 2023 Exam 1- Abnl pathways and related anatomy of schizophrenia ( With complete solution)

mesolimbic pathway correct answers subcortical part of the brain involved in cognition and emotion Name the dopamine pathways and the symptoms associated correct answers 1. NIGROSTRIATAL- to basal ganglia--movements 2. MESOLIMBIC- positive symptoms (assoc w/ euphoria and drug abuse 3.MESOCORTICAL-- with C's VTA-DLPFC - cognitive sympts; VTA-VMPFC- affective symptoms 4. TUBEROINFUNDIBULAR--hypothalamus to anterior pituitary; hyperprolactemia 5. THALAMIC --involved in deep sleep/arousal; no known abnl funct known in schizophrenia mesolimbic pathway. ?? correct answers VTA innervates parts of forebrain- nucleus accumbens, amygdala, prefrontal cortex, hippocampus mesolimbic pathway correct answers plays key and complex role in motivation, emotions and rewards What does REMM stand for? correct answers Rewards, emotion, motivation-mesolimbic mesolimbic pathway correct answers Responsible for the positive symptoms of schizophrenia positive symptoms correct answers Schizophrenic symptoms that involve behavioral excesses or peculiarities, such as hallucinations, delusions, bizarre behavior, and wild flights of ideas. Why do Schizophrenics have hallucunstions like being HIGH on cocaine? correct answers because dopamine is HIGH positive symptoms of schizophrenia correct answers caused by increase in dopamine positive symptoms of schizophrenia correct answers Delusions of reference, delusions of persecution, delusions of grandeur, thought broadcasting, though insertion, hallucinations, disorganized thought, disorganized behaviour, catatonia positive symptoms of schizophrenia correct answers reduced by D2 antagonist (Blockade) mesocortical pathway correct answers VTA to prefrontal cortex mesocortical pathway-dorsolateral prefrontal cortex correct answers cognition and executive function