NURS 660 Exam 1- Sum 2023 (Passed!)

dopamine hypothesis correct answers the theory that schizophrenia results from excessive activity of the neurotransmitter dopamine dopamine hypothesis- nigrostriatal pathway correct answers The nigrostriatal dopamine pathway that projects from the substantia nigra to the basal ganglia or striatum, is part of the extrapyramidal nervous system and controls motor function and movement. Mesolimbic dopamine hypothesis: Hyperactivity of dopamine neurons in the mesolimbic dopamine pathway cause what symptoms of schizophrenia correct answers symptoms of psychosis such as delusions and hallucinations. This pathway is also involved in pleasure, reward, and reinforcing behavior, and many drugs of abuse interact here. correct answers What conditions other than schizophrenia may cause positive symptoms? correct answers Depression, mania, dementia, drug-induced psychosis Hyperactivity of the _______________________________ pathway may also play a role in the hostility and aggression found with schizophrenia. correct answers mesolimbic dopamine pathway If there is too much dopamine in the basal ganglia causes what type of movements? correct answers chorea, dyskinesia and tics Deficiency iof dopamine in the basal ganglia can also causes what types of movement? correct answers akathisia and dystonia. When antipsychotics are given and dopamine is blocked in the tuberoinfundibular pathway what abnormalities will be seen? correct answers Hyperprolactemia leading to galactorrhea, amenorrhea, and sexual dysfunction. Cross-titration must occur over several days to weeks, otherwise the patient can develop what symptoms? correct answers Agitation, activation, insomnia, rebound psychosis, and withdrawal. . When cross titrating and the patient starts doing well while both drugs are present what should you do? correct answers A. Keep both drugs at the current dose and monitor the patient B. Continue with the cross titration in spite of the patient's improvement. Why should a patient not be maintained on 2 antipsychotics? correct answers All antipsychotics suppress dopamine and there is an increased risk of side effects If switching from a pine to a done, the pine should be stopped slowly over: