Test Bank - Immunology and Serology in Laboratory
Medicine, 7th Edition (Turgeon, 2023), Chapter 2
mimi
[COMPANY NAME] [Company address]
, Chapter 02: Antigens and Antibodies
Turgeon: Evolve Resources for Immunology & Serology in Laboratory Medicine, 7th Edition
MULTIPLE CHOICE
1. An antigen is described as a substance that
a. stimulates antibody formation.
b. has the ability to bind to an antibody.
c. is capable of stimulating an immune response.
d. All of the above.
ANS: D
An antigen is a substance that stimulates antibody formation and has the ability to bind to an
antibody. Foreign substances can be immunogenic or antigenic (capable of provoking an
immune response) if their membrane or molecular components contain structures recognized as
foreign by the immune system. These structures are called antigenic determinants or epitopes.
An epitope, as part of an antigen, reacts specifically with an antibody or T cell receptor.
DIF: Cognitive Level: II REF: p. 15
2. Cellular antigens of importance to immunologists include
a. histocompatibility antigens.
b. autoantigens.
c. blood group antigens.
d. All of the above.
ANS: D
Cellular antigens of importance to immunologists include histocompatibility antigens, autoantigens,
and blood group antigens.
DIF: Cognitive Level: I REF: p. 15
3. Another name for the major histocompatibility complex (MHC) in humans is
a. human leukocyte antigen.
b. allogenic antigens.
c. epitopes.
d. autoantigens.
ANS: A
The MHC is referred to as the human leukocyte antigen (HLA) system in humans because its gene
products were originally identified on white blood cells (WBCs, leukocytes).
DIF: Cognitive Level: I REF: p. 15
4. Haptens are characterized as being
Medicine, 7th Edition (Turgeon, 2023), Chapter 2
mimi
[COMPANY NAME] [Company address]
, Chapter 02: Antigens and Antibodies
Turgeon: Evolve Resources for Immunology & Serology in Laboratory Medicine, 7th Edition
MULTIPLE CHOICE
1. An antigen is described as a substance that
a. stimulates antibody formation.
b. has the ability to bind to an antibody.
c. is capable of stimulating an immune response.
d. All of the above.
ANS: D
An antigen is a substance that stimulates antibody formation and has the ability to bind to an
antibody. Foreign substances can be immunogenic or antigenic (capable of provoking an
immune response) if their membrane or molecular components contain structures recognized as
foreign by the immune system. These structures are called antigenic determinants or epitopes.
An epitope, as part of an antigen, reacts specifically with an antibody or T cell receptor.
DIF: Cognitive Level: II REF: p. 15
2. Cellular antigens of importance to immunologists include
a. histocompatibility antigens.
b. autoantigens.
c. blood group antigens.
d. All of the above.
ANS: D
Cellular antigens of importance to immunologists include histocompatibility antigens, autoantigens,
and blood group antigens.
DIF: Cognitive Level: I REF: p. 15
3. Another name for the major histocompatibility complex (MHC) in humans is
a. human leukocyte antigen.
b. allogenic antigens.
c. epitopes.
d. autoantigens.
ANS: A
The MHC is referred to as the human leukocyte antigen (HLA) system in humans because its gene
products were originally identified on white blood cells (WBCs, leukocytes).
DIF: Cognitive Level: I REF: p. 15
4. Haptens are characterized as being
