Multiple Sclerosis Test Questions with Correct Answers

Multiple Sclerosis Test Questions with Correct Answers MS definition - Answer-Chronic, disabling disease that attacks the central nervous system MS mechanism - Answer-Autoimmune MS lifespan - Answer-Normal Cost of MS per person over lifetime - Answer-2 million 3 Pathalogical findings of MS - Answer-CNS inflammation and demyelination, Axon damage (mainly myelin), Gray and white matter damage What else is lost in MS (other than myelin) - Answer--Axonal damage. -connections between axons, -Gray matter with myelin Plaques in MS mechanical properties - Answer-Harder and stiffer than non affected tissues What happens to form plaques in MS? - Answer-Scarring of tissue Perivascular cuffing definition - Answer-Inflammation around axons that leads to demyelination Onset of age MS - Answer-15-45 years Gender MS - Answer-70% women Race incidence MS - Answer-Much more in Caucasians. Occurs in areas far from the equator where Scandinavians settle What causes MS? What are 3 possibilities? - Answer-Not totally understood. Genetics, environment, autoimmune are the 3 factors. Risk of MS if you have a twin - Answer-Increase drastically Genetic risk factors MS (name the gene, and give other factors) - Answer-HLA DR gene, Being a twin (30%), 15% of patients have a family history of MS