NUR2474 Pharmacology Module 5 Quiz Review 2023 UPDATED
1. Physical dependence vs addiction with opiate use a. Tolerance i. Increased doses needed to obtain the same response ii. Develops with analgesia, euphoria, sedation, and respiratory depression iii. Cross-tolerance to other opioid agonists iv. No tolerance to miosis or constipation develops b. Physical dependence i. Abstinence syndrome with abrupt discontinuation ii. About 10 hours after last dose, the initial reaction occurs and includes yawning, rhinorrhea, and sweating iii. Progresses to violent sneezing, weakness, nausea, vomiting, diarrhea, abdominal cramps, bone and muscle pain, muscle spasms, and kicking movements iv. Lasts 7 to 10 days if untreated v. Withdrawal is unpleasant but not lethal, as it may be with CNS depressants vi. Patients dependence does not mean addiction vii. Short-term use does not lead to dependence viii. If used as prescribed, it does not lead to dependence. 1. Wean patient of medication slowly, and they will be fine. c. It is not common for patients to abuse opioids
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