CPPS 304 Pharmacology Exam Questions With Verified Answers.
CPPS 304 Pharmacology Exam Questions With Verified Answers. Receptor - Answer Macromolecule whose biological function changes when a drug binds to it What are the link between chemical actions and biological function? - Answer Receptors Emax - Answer maximum effect of a drug What happens when Emax is reached? - Answer Emax occurs when all receptors are bound What is in indication that spare receptors are present? - Answer When Emax is reached before all receptors are bound Agonist - Answer has affinity for a receptor as well as intrinsic activity at the receptor Antagonist - Answer has affinity for a receptor but no intrinsic activity at the receptor partial agonist - Answer has affinity for a receptor but lacks the full intrinsic activity of an agonist inverse agonist - Answer binds to a constitutively active receptor and inactivates it affinity - Answer the propensity of a ligand to bind to a receptor high affinity = - Answer binds readily to a receptor low affinity = - Answer spends less time bound to a given receptor intrinsic activity - Answer the action carried out by the ligand while it is bound to a receptor Kd - Answer dissociation constant (affinity of a drug for a receptor) What does the value of Kd signify? - Answer measures the propensity of a drug to release (dissociate) from a receptor .
Document information
- Uploaded on
- October 27, 2023
- Number of pages
- 4
- Written in
- 2023/2024
- Type
- Exam (elaborations)
- Contains
- Questions & answers
