In this example the original mutation that caused the huntington allele occurred in a

QUIZ WITH VERIFIED SOLUTION 2023-2024

QUIZ



Explain the connection between the founder and the G8-C marker.




Transcribed Image Text: II Ш IV (AB AA (AA (AB AB AB вс (AB AB (AB AB BC AB AB BC вB BC AC AA BC (CD) BB BC VI
AC (AB AC AC AC AC AA BC AA вс (AA вс вс VII AC вс вс FIGURE 25.7 The transmission pattern of a molecular marker for
Huntington disease. Affected members are shown with black symbols. The letters within each symbol indicate the forms
of the G8 marker (A, B, C, or D) the individual carries. Affected individuals always carry the C version of this marker. In rare
cases, an unaffected individual may also carry the G8-C marker. Symbols with slashes indicate deceased individuals.




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In this example the original mutation that caused the huntington allele occurred in a
germline cell or gamete in which the huntington allele was linked to the G8 C marker.This
diagram represents a small part of a much larger pedigree.The high frequency of the
huntington's disease gene in this population,some of the spouses of affected individuals
have also descended from the affected gene carriers.In none these cases ,however, was