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LIPOGÉNESIS LIPÓLISIS Y BETAOXIDACION

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Written in
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Se describe en esquemas la lipogénesis lipólisis y betaoxidación

Institution
Universidad Autónoma De Madrid
Course
Bioquímica Bàsica









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Institution
Universidad Autónoma de Madrid
Study
Medicina
Course
Bioquímica Bàsica
All documents for this subject (24)

Document information

Uploaded on
October 15, 2023
Number of pages
6
Written in
2023/2024
Type
Class notes
Professor(s)
Dra. villanela
Contains
All classes

Subjects

  • bioquimica
  • lipolisis
  • lipogenesis
  • betaoxidación
  • trigliceridos
  • insulina

Content preview

APUNTES DE
BIOQUIMICA
METABOLISMO DE
LIPIDOS (Acidos grasos y
trigliceridos)

, METABOLISMO DE
ACIDOS GRASOS
SINTESIS/LIPOGENESIS BREAKDOWN/BETA OXIDACION


Principal meta Formar acidos grasos Generar energia


Sitio Citoplasma Mitocondria


Hígado y tejido adiposo

Tejido musculo y otros tejidos
glandulas mamarias (Almacena
NO: cerebro que no usa lipidos, GR NO
en adipocitos)
tiene mitocondria


Precursor Acetil CoA Acyl Coa


Transportador Lanzadera de citrato Lanzadera de carnitina


Enzima que
Carnitina palmiotiltransferasa I /
determina la Acetil CoA carboxilasa
carnitina acyltransferasa I
velocidad


ATP
NAD+
Sustancias Biotina cofactor
FAD
requeridas CO2
H2O
NADPH


INSULINA
hiperglicemia
Regulacion ATP
glucagon indirectamente
positiva Estados de alta energia: ATP y
NADPH INH a la isocitrato
dehidrogenasa: +++ Citrato


glucagon hipoglicemia epinefrina Malonyl CoA (intermediario de
Regulacion
AMP y catecolaminas lipogenesis INH CAT I)
negativa
AcylCoA y palmitoil CoA Insulina (indirecto)


Acetil CoA
Productos Acido palmitico cuerpos cetonicos
finales NADP NADH+
FADH2
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