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OCR Biology A-Level Osmoregulation Summary

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Handwritten Notes detailing all the necessary A* content for Osmoregulation in OCR A-Level Biology.

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Maintenance of body
Osmoregulation the
optimum water
potential in the
:




Change in water levels Detected by the hypothalamus Negative feedback coordinated
:
->




ADH (Anti-Diuretic Hormone) :
Released from the pituitary gland triggers the production of CAMP
↳ cAmp Acts :

as a
secondary messenger causing a cascade of events :
:
Vesicles fuse in contact with
lining the collecting duct
with the cell surface membrane

the tissue fluid of the medulla
2 .
These vesicle membranes contain
aquaporins (water channels), making the membrane
more
permeable to water

3 .

Water can move out of the tubule cels bacu into the blood capillaries
↳ The more ADH released the ,
more water is reabsorbed
Urine
testing
:



·

hCG is
present in the urine of pregnant women

monoclonal antibodies Antibodies from :
a
single done of cens that
target specific chemicals
41 .
A mouse is
injected with hch so it produces the correct antibodies

2 The B-ceus removed from and fused with
myeloma Ccancer cell
.


are the a
spleen

newly formed
The
hybridoma divides
3
rapidly to produce monoclonal antibodies
.




Pregnancy Test :



1 .
The wich is soaked in urine

2
The hea bind antibodies forming
Urine will to the
nculantibody
.
in the a complex
.
3
These antibodies are also attached to a small coloured bead
4
Urine carries complex
along window
.

the to the test

5 Immobilised monoclonal antibodies will attach to the HCG antibody complex
only
.




↳ coloured line is shown

6 Coloured antibodies hCG will continue to a second line shows the test is
without
working
. ->




and alcohol urine
Drug testing Drug metabolites
pass through the
Lidneys into
:




:monoclonal antibodies will indicate
drug presence

↳was mromatography/massspectrometers
can confirm i set

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October 10, 2023
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2023/2024
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Summary
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