Immunology HMX Test Questions and Answers All Correct

Immunology HMX Test Questions and Answers All Correct dactylitis - Answer Inflammation of an entire digit (a finger or a toe), also referred to as 'sausage digit'. Enthesitis - Answer Inflammation of the site where a tendon or ligament inserts into a bone. Intertriginous - Answer Referring to areas where skin rubs together, such as under the armpits and in the groin. Lymphocytes - Answer Small leukocytes that are central players in the adaptive immune system. include T cells and B cells. Plasmacytoid dendritic cell (pDC) - Answer A type of dendritic cell that produces large amounts of type I interferon. TNFα - Answer A pro-inflammatory cytokine, often released by macrophages and dendritic cells early in acute inflammation. Type I interferon (type I IFN) - Answer A class of pro-inflammatory cytokines. group of cytokines that initiate signaling that activates the antiviral state. can be produced by most cells in the body, but pDCs are very efficient at producing these cytokines. innate immune system - Answer Exists before exposure to pathogens Capable of very rapid response Required to activate slower adaptive immune system Inflammation - Answer delivery of cells, proteins and fluid into infected or injured tissue, defense against microbes or repair of tissue Leukocytes (WBC) - Answer Neutrophils (polymorphonuclear leukocytes), Monocytes, Lymphocytes, Eosinophils, Basophils Tissues sentinel cells - Answer Immune cells residing in tissues like epithelium, secrete proinflammatory cytokines. Dendritic cells, Tissue resident macrophages, Mast cell Neutrophils (polymorphonuclear leukocytes) - Answer Leukocyte Receptors which can recognize molecules on the surface of microbes Innate immune receptors Microbes bind to the receptors, activating the cell Microbe is internalized and killed (phagocytosis) Are phagocytes After it kills the microbe it undergoes apoptosis Monocytes - Answer Leukocyte Changes once it enters the tissue to macrophage Very good at phagocytosis Works the same as the neutrophil Also eats dead cells, including apoptotic cells