BCH210 STUDY GUIDE QUESTIONS WITH COMPLETE SOLUTIONS

BCH210 STUDY GUIDE QUESTIONS
WITH COMPLETE SOLUTIONS
Which AA likes to form alpha helix? correct answer: Glutamate

Which AA likes to form beta sheet correct answer: Valine

Which amino acids have aliphatic side chains? correct answer:
alanine, glycine, valine, leucine, isoleucine,

which amino acids have aliphatic hydroxyl side chains? correct
answer: serine and threonine

which amino acids have aromatic side chains? correct answer:
phenylalanine, tyrosine, tryptophan

which amino acids are sulfur containing? correct answer:
cysteine and methionine

acidic amino acids? correct answer: asparagine, glutamine,
aspartate, glutamate

4 basic amino acids correct answer: lysine, arginine, histidine,

hydrophobic amino acids correct answer: alanine, glycine*,
valine, isoleucine, leucine, phenylalanine, methionine, proline

hydrophilic amino acids POLAR correct answer: asparagine,
glutamine, serine, threonine, cysteine*

, hydrophilic amino acids CHARGED correct answer: arginine,
lysine, histidine (basic), aspartic acid, glutamic acid

Amphipathic aromatic amino acids correct answer: tryptophan,
tyrosine

pKa of Arginine side chain correct answer: 12.5

pKa of Lysine side chain correct answer: 10.5

pKa of Cysteine side chain correct answer: 8.3

Histidine pkA side chain correct answer: 6

Glutamic acid pKa side chain correct answer: 4.3

Aspartic Acid side chain pKa correct answer: 3.9

Alpha Helix- N-H residue and C=O correct answer: N-H group
of residue i donates a H-bond back to the C=O group of residue
i-4

Features of the alpha helix:
a) residues p/turn
b) degrees between adjacent residues
c) rise p/residue
d) how many Å across backbone?
e) inter/intrastrand bonds? correct answer: a) 3.6
b) 100
c) 1.5