NBME 26 Exam Questions with 100% Correct Answers

Serum electrophoresis Correct Answer First peak is albumin Alpha 1 globulins = alpha antitrypsin, alpha 1 antichymotrypsin, TBG, Alpha 2 globulins = haptoglobulin, macroglobulin, ceruloplasmin, TBG, protein C, angiotensinogen Beta = beta 2 microglobin, plasminogen, angiostatins, SHBG, transferrin Gamma = Ig Serum electrophoresis in multiple myeloma Correct Answer gamma spike Serum electrophoresis blurring beta 2 and gamma regions Correct Answer increased CRP Increased iga A/w respiratory infections, arthritis, cirhosis Serum electrophoresis wide gamma region Correct Answer hypergammaglobulinemia A/w chronic liver disease, connective tissue disease, inflammatory disease Lesch Nyhan syndrome Correct Answer hypoxanthine-guanine phosphoribosyltransferase Aka hypoxanthine and guanine have defective salvage A/w rhabdomyolysis / compartment syndrome Correct Answer myoglobinuria & acute renal failure via acute tubular necrosis Anchoring fibrils Correct Answer type VII collagen; connecting basal lamina to reticular lamina Part of hemidesmosomes If defective - blistering can form Autoimmune hemolysis Correct Answer a/w CLL Anemia Reticulocytosis Unconjugate hyperbilirubinemia Spherocytes