NBME 26 Exam Questions with 100%
Correct Answers
Absence of the gamma region on SPEP indicates Correct Answer immunodeficiency
with hypogammaglobulinemia or agammaglobulienmia
increased left atrial pressure during ventricular systole on the pressure-time graph
indicates Correct Answer mitral regurgitation, likely from rupture of the chordae tendinae
Mannitol's effect on serum osmolality Correct Answer increases serum osmolality (and
in turn, triggers production of ADH)
hypoventilation is characterized by Correct Answer increased PaCO2
decreased O2
NORMAL A-a gradient
hypoxemia with normal A-a gradient Correct Answer hypoventilation
high altitude
hypoxemia with elevated A-a gradient Correct Answer V/Q mismatch
diffusion limitation (ie. fibrosis)
right-to-left shunt
septic arthritis vs osteoarthritis Correct Answer septic is acute; with inflammation,
redness, swelling
OA is chronic, progressive, with subchondral cysts and degeneration
what is the most likely rationale for inducing ventilation in a patient with a subdural
hematoma Correct Answer to cause cerebral vasoconstriction
this decreases cerebral blood flow and intracranial pressure
This rapidly and irreversibly causes platelet aggregation through its action on the P2Y1
and P2Y12 receptors Correct Answer ADP
abruptio placentae Correct Answer premature separation of the placenta from the
uterine wall prior to delivery; causes painful vaginal bleeding
Placenta accreta Correct Answer Improper implantation of placenta into the
myometrium with little or no intervening decidua; most commonly presents with retained
products of conception and postpartum hemorrhage
, pudendal nerve Correct Answer Supplies sensation to external genitalia and perineum
(external hemorrhoids, below dentate line); does NOT carry and PNS fibers
these nerves function to excite and contract the detrusor muscle of the bladder via
muscarininc AcH receptors while sympathetic nerves mediate relaxation of the internal
urethral sphincter via alpha-1 adrenergic receptors Correct Answer pelvic
parasympathetic nerves (same as pelvic splanchnics!)
splice site at start of intron Correct Answer typically GUAAG
ketogenesis decreases or increases in the starvation state? Correct Answer increases
Folate deficiency anemia Correct Answer INCREASED homocysteine
normal mma
Baclofen Correct Answer GABA-B receptor agonist
muscle relaxant
case series Correct Answer involves a small group of patients with a similar diagnosis
TB infects macrophages and leads to granuloma formation via the actions of - Correct
Answer IL-12 and IFN-gamma on macrophages
postprandial abdominal pain, melena, diaphoresis, and orthostatic hypotension in the
setting of a pancreatic or duodenal lesion indcates Correct Answer Zollinger-Ellison
syndrome; gastrinoma
medially, the precentral gyrus contains neurons that control - Correct Answer the lower
extremity
laterally, the precentral gyrus contains neurons that control - Correct Answer c/l face
Causes of NORMAL Anion Gap Metabolic Acidosis Correct Answer HARDASS
hyperchloremia/hyperalimentation
addison dz
renal tubular acidosis (RTA)
diarrhea
acetazolamide
spironolactone
saline infusion
Correct Answers
Absence of the gamma region on SPEP indicates Correct Answer immunodeficiency
with hypogammaglobulinemia or agammaglobulienmia
increased left atrial pressure during ventricular systole on the pressure-time graph
indicates Correct Answer mitral regurgitation, likely from rupture of the chordae tendinae
Mannitol's effect on serum osmolality Correct Answer increases serum osmolality (and
in turn, triggers production of ADH)
hypoventilation is characterized by Correct Answer increased PaCO2
decreased O2
NORMAL A-a gradient
hypoxemia with normal A-a gradient Correct Answer hypoventilation
high altitude
hypoxemia with elevated A-a gradient Correct Answer V/Q mismatch
diffusion limitation (ie. fibrosis)
right-to-left shunt
septic arthritis vs osteoarthritis Correct Answer septic is acute; with inflammation,
redness, swelling
OA is chronic, progressive, with subchondral cysts and degeneration
what is the most likely rationale for inducing ventilation in a patient with a subdural
hematoma Correct Answer to cause cerebral vasoconstriction
this decreases cerebral blood flow and intracranial pressure
This rapidly and irreversibly causes platelet aggregation through its action on the P2Y1
and P2Y12 receptors Correct Answer ADP
abruptio placentae Correct Answer premature separation of the placenta from the
uterine wall prior to delivery; causes painful vaginal bleeding
Placenta accreta Correct Answer Improper implantation of placenta into the
myometrium with little or no intervening decidua; most commonly presents with retained
products of conception and postpartum hemorrhage
, pudendal nerve Correct Answer Supplies sensation to external genitalia and perineum
(external hemorrhoids, below dentate line); does NOT carry and PNS fibers
these nerves function to excite and contract the detrusor muscle of the bladder via
muscarininc AcH receptors while sympathetic nerves mediate relaxation of the internal
urethral sphincter via alpha-1 adrenergic receptors Correct Answer pelvic
parasympathetic nerves (same as pelvic splanchnics!)
splice site at start of intron Correct Answer typically GUAAG
ketogenesis decreases or increases in the starvation state? Correct Answer increases
Folate deficiency anemia Correct Answer INCREASED homocysteine
normal mma
Baclofen Correct Answer GABA-B receptor agonist
muscle relaxant
case series Correct Answer involves a small group of patients with a similar diagnosis
TB infects macrophages and leads to granuloma formation via the actions of - Correct
Answer IL-12 and IFN-gamma on macrophages
postprandial abdominal pain, melena, diaphoresis, and orthostatic hypotension in the
setting of a pancreatic or duodenal lesion indcates Correct Answer Zollinger-Ellison
syndrome; gastrinoma
medially, the precentral gyrus contains neurons that control - Correct Answer the lower
extremity
laterally, the precentral gyrus contains neurons that control - Correct Answer c/l face
Causes of NORMAL Anion Gap Metabolic Acidosis Correct Answer HARDASS
hyperchloremia/hyperalimentation
addison dz
renal tubular acidosis (RTA)
diarrhea
acetazolamide
spironolactone
saline infusion
