NBME 11 Exam Questions with 100% Correct Answers

60 y/o man develops pain, erythema, and swelling of the right great toe + Serum uric acid concentration is 3x normal; What finding is most common in patients with this condition Correct Answer No specific enzyme or renal defect; "90% of patients are idiopathic b/c of underexcretion of uric acid" Sensation to pain and temperature is decreased throughout both upper extremities and across the shoulders to the neck; Where is the lesion? Correct Answer Anterior white commisure Lung biopsy specimen shows anaplastic, biphasic neoplasm that expresses calretinin and cytokeratin but not carcinoembryonic antigen Correct Answer Asbestos; Ferruginous bodies 79 y/o women presents with chest pain for the past 4 hours + Cardiac exam shows a systolic murmur at the apex and a regular rhythm + ECG shows ST-segment elevation in the anterolateral leads + Chest x-ray shows cardio silhouette; Diagnosis Correct Answer Acute Coronary syndrome; "Any condition brought on by a sudden reduction or blockage of blood to the heart" 35 y/o man has Parkinson disease + Genetic analysis shows two loss of function mutations in the parkin gene, which encodes a ubiquitin protein ligase; What pathologic process is most likely to occur? Correct Answer Accumulation of aggregated protein within the cytoplasm of neurons Patient has Crohns disease; Urinary excretion of radioactivity in this patient is more than in a healthy patient because of inflammation-associated changes in the integrity of what? Correct Answer Tight junctions Patient has kidney and bone marrow transplant + Monitoring the allograft post-transplantation shows good function despite the lack of treatment w/ immunosuppresive drugs; The transplanted bone marrow is most likely inducing which of the following immune phenomena? Correct Answer Tolerance What drug promotes gastric emptying and relieves nausea and vomiting? Correct Answer Metoclopramide Patient is on a drug regimen consisting of an NNRTI and two NRTIs; What explains the beneficial effects of NNRTI therapy? Correct Answer Blocking the replication of the HIV viral genome in host cells