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CPPS 306 Midterm questions with correct answers
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-Used to treat Parkinson's Disease -Crosses the Blood Brain Barrier (unlike dopamine) and is decarboxylated to dopamine -Given with a peripheral decarboxylase inhibitor to permit lower dose and to lower nausea and vomiting side effects -Side effects: orthostatic hypotension, sedation, confusion, hallucinations, psychosis -Gold standard of treatment Answer Levo-dopa Give with levodopa (Parkinsons) Inhibits DOPA-decarboxylase in periphery--increased levodopa in CNS Answer Carbidopa Parkinsons peripheral COMT inhibitor Answer Entacapone Parkinsons Peripheral COMT inhibitor Answer Tolcapone Parkinsons MAO-B inhibitor Answer Selegiline
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