NUR2474 Pharmacology Module 10 Questions Review
1. Review timeframes for fetus development (trimesters), and which timeframes are most critical a. Development: i. Conception through week 2 ii. Embryonic period: weeks 3-8 (Gross malformations produced by teratogens) iii. Fetal period: Week 9-delivery (functions disrupted with teratogen exposure b. Third trimester: renal blood flow is doubled and renal excretion is accelerated 2. FDA Pregnancy Risk Categories a. A: Safest b. B: More dangerous than A c. C: More dangerous than A and B d. D: More dangerous than A, B, and C e. X: Most dangerous; known to cause fetal harm 3. Alcohol effects on fetus development a. Placental drug transfer i. All drugs can cross the placenta ii. Some can cross more easily than others b. Adverse drug reactions during pregnancy i. Can adversely affect both pregnant patient and fetus ii. Some unique effects; 1. Heparin causes osteoporosis 2. Prostaglandins stimulate uterine contraction 3. Certain pain relievers used during delivery can depress respiration in the neonate. c. Birth defects i. Gross malformations 1. Cleft palate, clubfoot, and hydrocephalus ii. Neurobehavioral and metabolic anomalies
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