MN553 Pharmacology Unit 2 Quiz Download To Score A+
What properties affect the distribution of drugs drug size, charge, chemical structure, pH, molecular size, lipid or water solubility first pass metabolism metabolism by the liver following oral administration Phase 1 reactions Oxidation, reduction, hydrolysis or non-synthetic reactions that prepare the drug for further metabolism - to make the drug more water soluble Phase II reactions synthetic or conjugation reactions, something is added to drug to make it more water soluble and more easily excreted by the kidneys
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