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Exam (elaborations)

Development (4-nuclear reprogramming + 5-ASCs)fully solved 2023

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Development (4-nuclear reprogramming + 5-ASCs)fully solved 2023 What is potency? - correct answer a cell's ability to differentiate into other cell types (almost synonymous w competence) What is totipotency? - correct answer cells with competence to generate ANY type of cell What is pluripotency? - correct answer cells with competence to generate MOST types of cell What is bipotency? - correct answer cells with competence to generate TWO types of cell What is unipotency? - correct answer cells with competence to generate ONE type of cell What does the Waddington Landscape state? - correct answer > cell fate = more restricted w time > cell fate decisions = irreversible > potency decreases w time (but iPSCs show not necessarily the case) What did Hans Driesch do? - correct answer First to show each cell of a two-cell stage sea urchin is totipotent What did Hans Spemann do? - correct answer Used baby hair to constrict embryos and show that blastomeres in salamander embryos up are totipotent up to 16 cell stage What did Briggs + Kings do? - correct answer First to successfully transplant nuclei into eggs

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