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Samenvatting H10 "Biology A Global Approach, Global Edition", tenth edition

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Een samenvatting van hoofdstuk 10 van "Biology A Global Approach" de tiende druk van de global edition. Dit hoofdstuk gaat over de productie van ATP in cellen.

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Aantekeningen H10:

 De glycolyse en de citroenzuur cyclus beschrijven. (welke producten worden gevormd, waar vindt glycolyse en de
citroenzuur cyclus plaats)

 Substraat-niveau fosforylatie:
- Pi-groep wordt direct van een substraat molecuul gekoppeld aan ADP




-
 Reacties in glycolyse/citroenzuur cyclus:
- Glycolyse:
 C6H12O6 + 2 ADP + 2 Pi + 2 NAD+  2 C3H3O3- + 2 H2O + 2 ATP + 2 NADH + 2 H+
- Koppelreactie:
 2 C3H3O3- + 2 HS-CoA + 2 NAD+  2 C2H3OS-CoA + 2 NADH + 2 CO2
- Citroenzuurcyclus:
 2 C2H3OS-CoA + 4H2O + 2GDP + 2Pi + 2 FAD + 6 NAD+  4CO2 + 2GTP + 2FADH2 + 6NADH + 6H+ + 2 HS-CoA
- Samen:
 1 C6H12O6+ 2 ADP + 2 GDP+ 4 Pi + 10 NAD+ + 2 FAD € 6 CO2 + 2 ATP + 2 GTP + 10 NADH + 10 H+ + 2 FADH2
 NADH, H+ en FADH2 naar ETK

 Glycolyse
- Plaats: cytosol
- Geen zuurstof nodig
- Afbraak van 1 glucose molecuul tot 2 pyruvaat moleculen
 Totaal: 10 stappen in 2 fases
 Fase 1: stap 1-5
 Gebruik van 2 ATP
 Oxidatie van 1 Glucose tot 2 Glyceraldehyde-3-fosfaat (G-3-P)
 Stap 1: gebruik van 1 ATP
 Stap 3: gebruik van 1 ATP
 Fase 2: stap 6-10 (produceert 4 ATP)
 Productie van 4 ATP via substraat level fosforylatie
 Oxidatie van G-3-P tot pyruvaat
 Stap 7: 1 ATP per G-3-P wordt gevormd
 Stap 10: 1 ATP per G-3-P wordt gevormd
- Producten: 2 pyruvaat, 2 H2O, 2 ATP, 2 NADH en 2 H+

Connected book
 image
Neil A. Campbell, Lisa A. Urry Biology
Publisher: maart 2014 ISBN: 9781292008653 Edition: 10

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