PCOA Practice Questions Correct 100%
A prevalence study conducted from January 1 to December 31, 2017, on a population of 125,000 identified 500 cases of a disease. The incidence rate of this disease is 2 per 1,000. What percentage of the cases was newly diagnosed in 2017? A. 5% B. 50% C. 2% D. Answer cannot be calculated from this data set - ANSWERSC. 2% Of 125,000 people, there were a total of 500 cases. An incidence rate of 2 per 1,000 means 250 new cases per 125,000 people. Thus, 50% are new cases. What mechanism is most commonly responsible for causing Down syndrome? A. Translocation of the Philadelphia chromosome (9 and 22) B. Deletion of a portion of the short arm of chromosome 5 C. Nondisjunction during meiotic segregation D. Robertsonian translocation of chromosome 21 - ANSWERSC. Nondisjunction during meiotic segregation Most commonly, Down syndrome occurs as an error during cell division. Other causes, although less likely, are mosaicism and Robertsonian translocation of chromosomes 21 and 14. Which of the following is not part of the epidemiologic triad? A. Host B. Environment C. Agent D. Vector - ANSWERSD. Vector The epidemiologic triad consists of the host, the agent, and the environment. Which of the following statements is not true regarding green tea? A. The major dose-limiting ingredient of green tea extract appears to be caffeine B. Human studies demonstrate that 8-16 cups of green tea per day are safe and well tolerated C. Human data suggest that green tea extract is associated with significant liver injury D. Green tea is associated with lower systolic blood pressure, total cholesterol, and LDL-C in humans - ANSWERSC. Human data suggest that green tea extract is associated with significant liver injury In 2008, the Dietary Supplements Information Expert Committee (DSI EC) of the United States Pharmacopeial Convention systematically reviewed 216 case reports on green tea products, including 34 reports concerning liver damage, in response to concerns over hepatotoxicity related to green tea extract (GTE)-containing weight-loss products. The data suggest that liver-related adverse effects after GTE intake are rare.
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