Immunology HMX Question with answers rated A+ 2023

Immunology HMX Question with answers rated A+ 2023dactylitis Inflammation of an entire digit (a finger or a toe), also referred to as 'sausage digit'. Enthesitis Inflammation of the site where a tendon or ligament inserts into a bone. Intertriginous Referring to areas where skin rubs together, such as under the armpits and in the groin. Lymphocytes Small leukocytes that are central players in the adaptive immune system. include T cells and B cells. Plasmacytoid dendritic cell (pDC) A type of dendritic cell that produces large amounts of type I interferon. TNFα A pro-inflammatory cytokine, often released by macrophages and dendritic cells early in acute inflammation. Type I interferon (type I IFN) A class of pro-inflammatory cytokines. group of cytokines that initiate signaling that activates the antiviral state. can be produced by most cells in the body, but pDCs are very efficient at producing these cytokines. innate immune system Exists before exposure to pathogens Capable of very rapid response Required to activate slower adaptive immune system Inflammation delivery of cells, proteins and fluid into infected or injured tissue, defense against microbes or repair of tissue Leukocytes (WBC) Neutrophils (polymorphonuclear leukocytes), Monocytes, Lymphocytes, Eosinophils, Basophils Tissues sentinel cells Immune cells residing in tissues like epithelium, secrete proinflammatory cytokines. Dendritic cells, Tissue resident macrophages, Mast cell Neutrophils (polymorphonuclear leukocytes) Leukocyte Receptors which can recognize molecules on the surface of microbes Innate immune receptors Microbes bind to the receptors, activating the cell Microbe is internalized and killed (phagocytosis) Are phagocytes After it kills the microbe it undergoes apoptosis