NUR 311 Final Exam Questions with Correct Answers (100% verified)

How do drugs affect the elderly? Correct Answer many drugs are metabolized slowly, have a longer action and are more likely to accumulate What are patient related variables to drug absorption and action? Correct Answer age, weight, the individual drug response (pharmacogenetics), ethnicity, sex What are drug related variables to drug absorption and action? Correct Answer dosage, route of admin, drug-diet interactions, drug-drug interactions four components of pharmacokinetics Correct Answer 1. Absorption 2. Distribution 3. Metabolism 4. Excretion A type of warning that appears in a drug's prescribing information and is required by the U.S. Food and Drug Administration (FDA) to alert prescribers of serious adverse events that have occurred with the given drug Correct Answer black box warning The ___________ enforces the controlled substances act Correct Answer DEA The most severe adverse effect of HMG-CoA reductase inhibitors (statins) Correct Answer rhabdomyolysis ____________ can injure muscle tissue, resulting in muscle pain, weakness and aches Correct Answer statins adverse effects of HMG-CoA reductase inhibitors (statins) Correct Answer nausea constipation diarrhea abd cramps headache mechanism of action of cholestyramine (bile acid sequestrant) Correct Answer binds to bile acids on the intestinal lumen, causing the bile acids to be excreted in the feces Use of cholestyramine (bile acid sequestrant) Correct Answer used as a *combination drug* to reduce LDL cholesterol T/F cholestyramine (bile acid sequestrant) is used as monotherapy for the treatment of elevated cholesterol Correct Answer false; used in combo with fibrates of statins