Combined Immunology HMX (All possible questions with complete solutions)
______________________ is the transfer of tissue/organ from one individual to another correct answers Transplantation _________________________ is the transfer of blood cells/blood products from one individual to another correct answers Transfusion _________________ transplant is the most common transplantation correct answers kidney _____________________ transfusion is the most common transfusion correct answers red blood cell Individuals who are not identical twins differ in many genes that they do not inherit. This means individuals will have different proteins based on these different genes. These differences are called ______________________ correct answers polymorphisms In transplantation, if one person is a donor and another is a recipient, then there might be a difference in proteins between each person. So, when an organ is transplanted, the recipient's immune system can detect the transplanted cells as non-self and lead an attack against them. This attack involves ________________ and ____ cells and is called an ___________________ ________________ _______________ correct answers antibodies T cells allogeneic immune response The recipient's T cells and antibodies that enter the implanted organ after transplantation cause inflammation in the organ as if the organ is a foreign invader, like a microbe. This leads to injury/death of the implanted organ. This is called _________________ _______________ correct answers transplant rejection The most polymorphic genes in our entire genome are the _____________________ ___________________ _________________ genes. correct answers major histocompatibility complex (aka HLA genes) MHC class II has the variants: __________, __________, and _________ proteins correct answers DP DQ DR MHC class I has the variants: ____________, ______________ and _________ correct answers A B C
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