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Concepts of Women’s and Men’s Health, Infections, and Hematologic Disorders:

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Scenario 1: Polycystic Ovarian Syndrome (PCOS) 1. What is the pathogenesis of PCOS? PCOS is a complex heterogeneous familial disorder characterized by anovulation, menstrual dysfunction, and signs of hyperandrogenism. Despite the exact pathophysiology of this disorder being unknown, studies show that PCOS can develop because of abnormal functioning of the hypothalamic-pituitary-ovarian (HPO) axis (Zeng et al., 2020). Inappropriate secretion of gonadotropin hormone due to ovarian dysfunction has been reported among PCOS patients. General the pathogenesis of PCOS is associated with neuroendocrine alterations, primary ovarian abnormalities, interactions of epigenetic and genetic changes, and endocrine and metabolic modifiers like insulin resistance, hyperinsulinemia, anti-Müllerian hormone, and adiposity.

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Week 10: Concepts of Women’s and Men’s Health, Infections, and Hematologic Disorders:

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Concepts of Women’s and Men’s Health, Infections, and Hematologic Disorders:

Knowledge Check

Scenario 1: Polycystic Ovarian Syndrome (PCOS)

1. What is the pathogenesis of PCOS?

PCOS is a complex heterogeneous familial disorder characterized by anovulation,

menstrual dysfunction, and signs of hyperandrogenism. Despite the exact

pathophysiology of this disorder being unknown, studies show that PCOS can develop

because of abnormal functioning of the hypothalamic-pituitary-ovarian (HPO) axis (Zeng

et al., 2020). Inappropriate secretion of gonadotropin hormone due to ovarian

dysfunction has been reported among PCOS patients. General the pathogenesis of PCOS

is associated with neuroendocrine alterations, primary ovarian abnormalities,

interactions of epigenetic and genetic changes, and endocrine and metabolic modifiers

like insulin resistance, hyperinsulinemia, anti-Müllerian hormone, and adiposity.

2. How does PCOS affect a woman’s fertility or infertility?

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  • infections
  • concepts of women’s and men’s health
  • and hematologic disorders
  • polycystic ovarian syndrome pcos
  • what is the pathophysiology of this disorder being unknown
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