NBME CBSE STUDY GUIDE/ TEST BANK
NBME CBSE STUDY GUIDE/ TEST BANK Type II pneumocytes surfactant (lecithin) Proliferate after injury Type I progenitors Neonatal Respiratory Distress Syndrome Polio live v killed vaccine Killed = Salk = IgG Live = Sabin = IgG + IgA - can be shed in feces Neonatal Respiratory Distress: Etiology + Tx Maternal DM (high insulin) or C-section (low cortisol) TX: dexamethasone before birth Lung maturity determined with Amniocentesis of Phospholipids (*type II pneumocytes) L S Type I pneumocytes Squamous gas diffusion Elastase in lungs macrophage: lysosomes PMN: azuronphilic granules Elastin stretches and recoils due to Lysine interchain crosslinks air pressure and intrapleural pressure at FRC Air pressure = 0 Intrapleural pressure = -5 Pulm Vasc Resistance is lowest during Exhale of Tidal Volume Lung Compliance is decreased by LHF, pulmonary edema, pulmonary fibrosis Lung Compliance is increased by emphysema, age Obesity affects ERV and FRC DECREASE ERV & FRC Blood flow/min (pulmonary v systemic) pulmonary = systemic Anatomic pulmonary shunt
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