SOLUTION MANUAL FOR CLAYTON 'S BASIC PHARMACOLOGY FORNURSES, 18TH EDITIONBY MICHELLE J. WILLIHNGANZ, MS, RN, CNE,SAMUEL L. GUREVITZ, PHARMD, CGP AND BRUCE D. CLAYTON

SOLUTION MANUAL FOR CLAYTON 'S BASIC PHARMACOLOGY FORNURSES, 18TH EDITIONBY MICHELLE J. WILLIHNGANZ, MS, RN, CNE,SAMUEL L. GUREVITZ, PHARMD, CGP AND BRUCE D. CLAYTON TABLE OF CONTENTS. Unit 1: Applying Pharmacology to Nursing Practice 1. Drug Definitions, Standards, and Information Sources 2. Basic Principles of Drug Action and Drug Interactions 3. Drug Action Across the Life Span 4. The Nursing Process and Pharmacology 5. Patient Education to Promote Health Unit 2: Illustrated Atlas of Medication Administration 6. Principles of Medication Administration and Medication Safety 7. Percutaneous Administration 8. Enteral Administration 9. Parenteral Administration: Safe Preparation of Parenteral Medications 10. Parenteral Administration: Intradermal, Subcutaneous, and Intramuscular Routes 11. Parenteral Administration: Intravenous Route Unit 3: Drugs Affecting the Autonomic and Central Nervous Systems 12. Drugs Affecting the Autonomic Nervous System 13. Drugs Used for Sleep 14. Drugs Used for Neurodegenerative Disorders (NEW!) 15. Drugs Used for Anxiety Disorders 16. Drugs Used for Depressive and Bipolar Disorders 17. Drugs Used for Psychoses 18. Drugs Used for Seizure Disorders 19. Drugs Used for Pain Management Unit 4: Drugs Affecting the Cardiovascular System 20. Introduction to Cardiovascular Disease and Metabolic Syndrome 21. Drugs Used to Treat Dyslipidemias 22. Drugs Used to Treat Hypertension 23. Drugs Used to Treat Dysrhythmias 24. Drugs Used to Treat Angina Pectoris 25. Drugs Used to Treat Peripheral Vascular Disease 26. Drugs Used to Treat Thromboembolic Disorders 27. Drugs Used to Treat Heart Failure 28. Drugs Used for Diuresis Unit 5: Drugs Affecting the Respiratory System 29. Drugs Used to Treat Upper Respiratory Disease 30. Drugs Used to Treat Lower Respiratory Disease Unit 6: Drugs Affecting the Digestive System 31. Drugs Used to Treat Oral Disorders 32. Drugs Used to Treat Gastroesophageal Reflux and Peptic Ulcer Disease 33. Drugs Used to Treat Nausea and Vomiting 34. Drugs Used to Treat Constipation and Diarrhea Unit 7: Drugs That Affect the Endocrine System 35. Drugs Used to Treat Diabetes Mellitus 36. Drugs Used to Treat Thyroid Disease 37. Corticosteroids 38. Gonadal Hormones Unit 8: Drugs Affecting the Reproductive System 39. Drugs Used in Obstetrics 40. Drugs Used in Men’s and Women’s Health Unit 9: Drugs Affecting Other Body Systems 41. Drugs Used to Treat Disorders of the Urinary System 42. Drugs Used to Treat Glaucoma and Other Eye Disorders 43. Drugs Used to Treat Cancer 44. Drugs Used to Treat the Musculoskeletal System 45. Drugs Used to Treat Infection Unit 10: Drugs Affecting the General Health of the Body 46. Nutrition 47. Herbal and Dietary Supplemental Therapy 48. Substance Abuse Chapter 1: Drug Definitions, Standards, and Information SourcesTest Bank MULTIPLE CHOICE 1. What is the name under which a drug is listed by the U.S. Food and Drug Administration (FDA)? a. Brand b. Nonproprietary c. Official d. Trademark ANS: C The official name is the name under which a drug is listed by the FDA. The brand name, or trademark, is the name given to a drug by its manufacturer. The nonproprietary, or generic, name is provided by the U.S. Adopted Names Council. DIF: Cognitive Level: Knowledge REF: p. 1 OBJ: 2 TOP: Nursing Process Step: Assessment MSC: NCLEX Client Needs Category: Safe, Effective Care Environment 2. Which source contains information specific to nutritional supplements? a. USP Dictionary of USAN & International Drug Names b. Natural Medicines Comprehensive Database c. United States Pharmacopoeia/National Formulary (USP NF) d. Drug Interaction Facts ANS: C United States Pharmacopoeia/National Formulary contains information specific to nutritional supplements. USP Dictionary of USAN & International Drug Names is a compilation of drug names, pronunciation guide, and possible future FDA approved drugs; it does not include nutritional supplements. Natural Medicines Comprehensive Database contains evidence based information on herbal medicines and herbal combination products; it does not include information specific to nutritional supplements. Drug Interaction Facts contains comprehensive information on drug interaction facts; it does not include nutritional supplements. DIF: Cognitive Level: Knowledge REF: p. 2 OBJ: 4 TOP: Nursing Process Step: Assessment MSC: NCLEX Client Needs Category: Physiological Integrity 3. What is the most comprehensive reference available to research a drug interaction? a. Drug Facts and Comparisons b. Drug Interaction Facts c. Handbook on Injectable Drugs d. Martindale—The Complete Drug Reference ANS: B First published in 1983, Drug Interaction Facts is the most comprehensive book available on drug interactions. In addition to monographs listing various aspects of drug interactions, this information is reviewed and updated by an internationally renowned group of physicians and pharmacists with clinical and scientific expertise. DIF: Cognitive Level: Comprehension REF: p. 3 OBJ: 3 TOP: Nursing Process Step: Assessment MSC: NCLEX Client Needs Category: Physiological Integrity 4. The physician has written an order for a drug with which the nurse is unfamiliar. Which section of the Physicians’ Desk Reference (PDR) is most helpful to get information about this drug? a. Manufacturer‟ssection b. Brand and Generic Name section c. Product Category section d. Product Information section ANS: B A physician‟s order would include the brand and/or generic name of the drug. The alphabetic index in the PDR would make this section the most user friendly. Based on a physician‟s order, manufacturer‟s information and classification information would not be known. The Manufacturer‟s section is a roster of manufacturers. The Product Category section lists products subdivided by therapeutic classes, such as analgesics, laxatives, oxytocics, and antibiotics. The Product Information section contains reprints of the package inserts for the major products of manufacturers. DIF: Cognitive Level: Comprehension REF: p. 3 OBJ: 4 TOP: Nursing Process Step: Planning MSC: NCLEX Client Needs Category: Physiological Integrity 5. Which online drug reference makes available to health care providers and the public a standard, comprehensive, up to date look up and downloadable resource about medicines? a. American Drug Index b. American Hospital Formulary c. DailyMed d. Physicians’ Desk Reference (PDR) ANS: C DailyMed makes available to health care providers and the public a standard, comprehensive, up to date look up and downloadable resource about medicines. The American Drug Index is not appropriate for patient use. The American Hospital Formulary is not appropriate for patient use. The PDR is not appropriate for patient use. DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 5 TOP: Nursing Process Step: Implementation MSC: NCLEX Client Needs Category: Physiological Integrity 6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing? a. Federal Food, Drug, and Cosmetic Act (1938) b. Durham Humphrey Amendment (1952) c. Controlled Substances Act (1970) d. Kefauver Harris Drug Amendment (1962) ANS: A The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the safety of all drugs before marketing. Later amendments and acts helped tighten FDA control and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs that cannot be used safely without medical supervision and restricts their sale to prescription by a licensed practitioner. The Controlled Substances Act addresses only controlled substances and their categorization. The Kefauver Harris Drug Amendment ensures drug efficacy and greater drug safety. Drug manufacturers are required to prove to the FDA the effectiveness of their products before marketing them. DIF: Cognitive Level: Knowledge REF: p. 4 OBJ: 8 TOP: Nursing Process Step: Assessment MSC: NCLEX Client Needs Category: Physiological Integrity 7. Meperidine (Demerol) is a narcotic with a high potential for physical and psychological dependency. Under which classification does this drug fall? a. I b. II c. III d. IV ANS: B Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lead to severe psychological and physical dependence. Schedule I drugs have high potential for abuse and no recognized medical use. Schedule III drugs have some potential for abuse. Use may lead to low to moderate physical dependence or high psychological dependence. Schedule IV drugs have low potential for abuse. Use may lead to limited physical or psychological dependence. DIF: Cognitive Level: Comprehension REF: p. 4 | p. 5 OBJ: 7 TOP: Nursing Process Step: Assessment MSC: NCLEX Client Needs Category: Safe, Effective Care Environment