Braun Applied Pathophysiology: Chapter 5 (Infection
Microbes - include bacteria, virus, fungi, protozoa Resident flora - Microorganisms that live on or within body's nonsterile areas without causing harm Resident flora compete with: - disease-producing microorganisms to protect the body against infections and to provide a type of natural immunity Destroying one type of resident flora can allow overproliferation of another competing type, for example: - Vaginal yeast infection in women who are on antibiotics Pathogens - Pathogen is a disease-producing microbe Pathogen causes disease by: - -Direct destruction of the host cell -Interfering with host cell metabolism -Exposing host cells to toxins Virulence - is the potency of the pathogen Coinfection - hosting two or more pathogens simultaneously Superinfection - infection arises in addition to one that is already present. Bacteria - -Single-celled
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