Preparing for ASCP(SBB) BOC PRACTICE QUESTIONS WITH COMPLETE SOLUTIONS

Chemicals that send signals between cells are Correct Answer: Cytokines Antibodies are made by what cells? Correct Answer: Plasma cells Where do B cells mature? Correct Answer: Bone Marrow Where do T cells mature? Correct Answer: Thymus Coating of a cell with antibodies or complement is called? Correct Answer: Opsonization CD4 + cells are? Correct Answer: T helper cells The specific chemical group that provokes an antibody response Correct Answer: Epitope Blood groups are made of two main kinds of chemicals Correct Answer: Proteins, carbohydrates What is the function of the FC piece of an immunoglobulin? Correct Answer: Monocyte binding What is the only Ig that crosses the placenta? Correct Answer: IgG What does 2-ME OR DTT do to IgM antibodies? Correct Answer: Destroys disulfide bonds Which is the secretory Ig? Correct Answer: IgA Which Ig is responsible for allergic reaction's? Correct Answer: IgE Which IgG subclass does not bind complement? Correct Answer: IgG4 Which IgG sub classes are most clinically significant? Correct Answer: IgG 1 & 3 What is isotype switching? Correct Answer: Example IgM switches to IgG What is the end point of complement activation? Correct Answer: Hole in cell At what stage of complement cascade is it amplified? Correct Answer: C3 activation What two ions are needed for complement activity? Correct Answer: Ca++ and Mg++ Name two complement components that are anaphylatoxins Correct Answer: C3a and C5a What is the minimum number of days a BBK specimen must be kept? Correct Answer: Seven days post transfusion