Pathophysiology : The Biologic Basis for Disease in Adults and Children: Chapter 9: Alterations in Immunity and Inflammation
Inappropriate Immune Responses may be - 1. allergy: exaggerated against environmental antigens 2. autoimmunity: misdirected against the host's own cells 3. alloimmunity: directed against beneficial foreign tissues, such as transfusions or transplants 4. immune deficiency: insufficient to protect the host Which is the most common and least threatening inappropriate immune response? - allergy hypersensitivity - an altered immunologic response to an antigen that results in disease or damage to the hose Which 2 ways can hypersensitivity be classified? - 1. by source 2. by mechanism allergy - -deleterious effects of hypersensitivity to environmental changes -hypersensitivity response against environmental antigen, most are Type I immunity - protective responses to antigens expressed by disease causing agents autoimmunity - -a disturbance in the immunological tolerance of self-antigens -body's immune system begins to recognize self antigens as foreign
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